Extracorporeal Photopheresis (ECP)
Extracorporeal photopheresis (ECP) is used, among other things, to treat amyotrophic lateral sclerosis (also known as ALS, myatrophic lateral sclerosis, Charcot disease or Lou Gehrig’s syndrome). In extracorporeal photopheresis, the white blood cells are collected in a bag by cell separation, a so-called apheresis. The collection takes about 2 hours. The cells are then treated with methoxsalen, which makes the cells sensitive to UV light and then irradiated with UV-A light. This radiation destroys the ALS cells. The remaining white blood cells are transfused back to the patient in an IV.
ECP therapy is used successfully for the following indications:
- Progressive systemic scleroderma
- T cell leukemia
- T cell lymphomas
- Systemic Lupus Erythematosus
- Crohn’s disease
- Autoimmune diabetes
- Sézary syndrome
- rejection reactions in organ transplants
- Graft-versus-host disease (GvHD)
- Pemphigus vulgaris
- Rheumatoid Arthritis
- B cell leukemia
- Ulcerative colitis
- dermatological diseases
- after bone marrow transplants
The ECP treatment takes about 2-3 hours and takes place on an outpatient basis on two consecutive days. Depending on the severity of the disease and the response, the treatment is initially carried out after 14 days, then at longer intervals depending on the course.
The aim of the well-tolerated therapy with few side effects is to remove the ALS cells so that the blockage in the extrapyramidal nerve tracts is stopped.
Find out more about the ECP:
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Do you have any questions or would you like further information? Then you are welcome to write to us or call us.
Our staff will answer your request quickly and competently. We will also be happy to call you back by telephone to provide you with individual advice.
Please write to us. We are gladly there for you.